Reactions of Chiral Phosphorous Acid Diamides: The Asymmetric Synthesis of Chiral α-Hydroxy Phosphonamides, Phosphonates, and Phosphonic Acids

DOI: 10.1021/jo00109a025

Source and publish data:

Journal of Organic Chemistry p. 931 - 940 (1995)

Update date:2022-08-02

Topics:

Authors:

Blazis, Vincent J.

Koeller, Kevin J.

Spilling, Christopher D.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00109a025

Addition of aldehydes to the anions of chiral phosphorous acid diamides in THF solution gave α-hydroxy phosphonamides in good yield.The diastereoselectivity was strongly dependent upon the diamide used and ranged from poor to good.The phosphorous acid dia

Full text of DOI:10.1021/jo00109a025

Products guided by the article

Product name:2-(1'-Hydroxy-3'-phenyl-(E)-prop-2'-enyl)-2,3,3a,4,5,6,7,7a-octahydro-1,3-bis(2,2-dimethylpropyl)-1H-1,3,2-benzodiazaphosphole 2-oxide

Cas No:162680-99-1

R&D Labs maybe for 162680-99-1

Chengdu Baishixing Science and Technology Industry Co., Ltd.

website:http://www.cd-bsx.com

Contact:+86-28-88531548

Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
Lianyungang Ningkang Chemical Co., Ltd

Contact:.+86-518-88588008

Address:http://www.chemnk.com
Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Hangzhou J&H Chemical Co., Ltd.

website:http://www.jhechem.com/

Contact:+86-571-87396432

Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Relevant to this article

General Synthesis of Tri-Carbo-Substituted N²-Aryl-1,2,3-triazoles via Cu-Catalyzed Annulation of Azirines with Aryldiazonium Salts

Doi:10.1021/acs.joc.0c01433
(2020)
Doi:10.1007/BF00486943
()
Novel N-acyl/aroyl-2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazides: Synthesis and characterization

Doi:10.3906/kim-1307-13
(2014)
Syntheses of 1-alkyl-1,25-dihydroxyvitamin D₃

Doi:10.1021/jo00111a047
(1995)
Metal-free synthesis of 1,3,5-trisubstituted benzenes by the cyclotrimerization of enaminones or alkynes in water

Doi:10.1039/c4ra00475b
(2014)
One pot synthesis of thiazolodihydropyrimidinones and evaluation of their anticancer activity

Doi:10.1016/j.ejmech.2004.06.001
(2004)

Article Doi