
Journal of Medicinal Chemistry p. 1751 - 1761 (1995)
Update date:2022-08-03
Topics:
Morelock
Pargellis
Graham
Lamarre
Jung
The on and off rate constants (k(on) and k(off)) were determined for a series of peptidomimetic, competitive inhibitors of human renin using a novel binding assay. The method entails analyzing a pair of ligand exchange reactions in which a dansylated inhi
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