Studies on a novel, potent and orally effective cholecystokinin A antagonist, FK-480. Synthesis and structure-activity relationships of FK-480 and related compounds

DOI: 10.1248/cpb.42.2071

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2071 - 2083 (1994)

Update date:2022-07-30

Topics:

Authors:

Satoh Satoh

Matsuo Matsuo

Sogabe Sogabe

Itoh Itoh

Tada Tada

Kinoshita

Yoshida Yoshida

Takaya Takaya

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.2071

We prepared various novel tricyclic 1,4-benzodiazepine derivatives as cholecystokinin (CCK) A antagonists, which were evaluated preliminarily for inhibition of ¹²⁵I-CCK-8 binding to rat pancreatic membranes in vitro and inhibiting effect on CCK

Full text of DOI:10.1248/cpb.42.2071

NII-Electronic Library Service

Products guided by the article

Product name:(3,4-Dihydro-2H-benzo[1,4]thiazin-5-yl)-(2-fluoro-phenyl)-methanone

Cas No:163155-61-1

R&D Labs maybe for 163155-61-1

Ningbo Huajia Chemicals

Contact:+86-574-87065746

Address:10th Floor, No.787 Baizhang East Road,
GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Jinzhou Jiutai Pharmaceutical Co.,Ltd

Contact:+86-0416-5179890

Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Okeanos Tech.Co.,LTD

Contact:+86-10-62651721

Address:29 Yongxing Road, Daxing District,Beijing China
Shanghai Kangxin Chemical Co., Ltd

Contact:+86 21 60717227

Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai

Relevant to this article

Doi:10.1016/0008-6215(67)85013-4
(1967)
Design, synthesis, structure-activity relationship and insecticidal activities of trifluoromethyl-containing sulfiliminyl and sulfoximinyl phthalic acid diamide structure

Doi:10.1002/cjoc.201400223
(2014)
A general synthetic route to anomeric α-azido and α-amino acids and formal synthesis of (+)-hidantocidin

Doi:10.1021/jo00103a057
(1994)
Antibody-catalyzed rearrangement of a peptide bond: Mechanistic and kinetic investigations

Doi:10.1021/ja00122a001
(1995)
Polycyclic N-heterocyclic compounds 76: Synthesis and antiplatelet evaluation of 2,4-disubstituted 5,6-Dihydro[1]benzofuro[3′,2′:2,3] oxepino[4,5-d]pyrimidines

Doi:10.1002/jhet.1539
(2014)
Aromatic phosphonate-phosphines

Doi:10.1080/10426509608038791
(1996)

Article Doi