Synthesis of the C(3)-C(15) segment of rutamycin B via a C(8)-C(9) fragment assembly aldol reaction: Metal dependence of the aldehyde and enolate diastereofacial selectivities

DOI: 10.1016/0040-4039(95)00628-P

Source and publish data:

Tetrahedron Letters p. 3447 - 3450 (1995)

Update date:2022-07-30

Topics:

Authors:

Gustin, Darin J.

VanNieuwenhze, Michael S.

Roush, William R.

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Article abstract of DOI:10.1016/0040-4039(95)00628-P

The diastereofacial selectivities of aldehyde 2b and ketone 3 are metal dependent, and their fragment assembly aldol coupling is a matched double asymmetric reaction when a chlorotitanium enolate is used.

Full text of DOI:10.1016/0040-4039(95)00628-P

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