Synthesis of the C(3)-C(15) segment of rutamycin B via a C(8)-C(9) fragment assembly aldol reaction: Metal dependence of the aldehyde and enolate diastereofacial selectivities

DOI: 10.1016/0040-4039(95)00628-P

Source and publish data:

Tetrahedron Letters p. 3447 - 3450 (1995)

Update date:2022-07-30

Topics:

Authors:

Gustin, Darin J.

VanNieuwenhze, Michael S.

Roush, William R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)00628-P

The diastereofacial selectivities of aldehyde 2b and ketone 3 are metal dependent, and their fragment assembly aldol coupling is a matched double asymmetric reaction when a chlorotitanium enolate is used.

Full text of DOI:10.1016/0040-4039(95)00628-P

Products guided by the article

Product name:(2S,3R,4S,6R,7S,8S,9S,10R,11S,12R)-3-Benzyloxy-1,11-bis-(tert-butyl-dimethyl-silanyloxy)-13-(tert-butyl-diphenyl-silanyloxy)-7-hydroxy-9-methoxymethoxy-2,4,6,8,10,12-hexamethyl-tridecan-5-one

Cas No:163936-51-4

R&D Labs maybe for 163936-51-4

Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
ANTAI BIO-TECH CO LTD

website:http://www.antaibio.com

Contact:0086-21-65663057

Address:Room 2108, Building 2，No. 489 Zhengli Road，200433
Zibo Fuxi'er Chemical Co.,Ltd （Shanxian Fuxi'er Chemical Co.,Ltd）

Contact:+86-533-2091422

Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China
Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province

Relevant to this article

Chiral derivatives of 1,2-benzenedisulfonimide as efficient Bronsted acid catalysts in the Strecker reaction

Doi:10.1039/c4ob00552j
(2014)
Direct condensation of functionalized sp³ carbons with formanilides for enamine synthesis using an in situ generated HMDS amide catalyst

Doi:10.1039/c4cc02228a
(2014)
A shuttle for the transport of protons based on a [2]rotaxane

Doi:10.1002/ejoc.201402249
(2014)
Synthesis of substituted imidazolidines: Base-stable precursors of 4,5-dihydro-1h-imidazol-3-ium salts and N-heterocyclic carbenes

Doi:10.1002/ejoc.201402364
(2014)
Synthesis and properties of ultralow dielectric porous polyimide films containing adamantane

Doi:10.1002/pola.28928
(2018)
N-Boc 2-acyloxazolidines: Useful precursors to enantiopure 1,2-diols via highly diastereoselective nucleophilic additions

Doi:10.1016/0040-4020(95)00145-X
(1995)

Article Doi