Tetrahedron Letters p. 5225 - 5228 (1994)
Update date:2022-07-30
Topics:
Lebreton, Jacques
Waldner, Adrian
Fritsch, Valerie
Wolf, Romain M.
De Mesmaeker, Alain
The two isomeric amide modifications 1 and 2 show similar effects on the melting temperature of RNA/DNA duplexes, when they replace the natural phosphodiester linkage in the DNA strand. The synthesis of the amide dimer 1 is presented.
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