Tetrahedron p. 2255 - 2260 (1987)
Update date:2022-09-26
Topics:
Moehrle, H.
Wehefritz, B.
Steigel, A.
The aminolysis of Z-α-halogenoacetophenone oximes results in different mixtures of E- and Z-α-aminoacetophenone oximes depending on the solvent used.Assignment of configuration can be achieved by 13C NMR spectroscopy even if only one isomer is available using a strong solvent dependence of the methylene chemical shift in the case of the Z-isomers.This effect is due to the presence of different conformations in the solvents chloroform and dimethyl sulfoxide.Together with a study by vapor pressure osmometry the results provide an unambiguous proof of intramolecular hydrogen bonding of Z-α-aminoacetophenone oximes in chloroform.
View MoreTianjin Ingenochem Technology Co.,Ltd
Contact:+86-22-23677060
Address:Hitech Green Industry Park K2-9-602, Nankai district
Contact:+65 9658 0999
Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
Contact:+86-531-58668191 58668193 58668196 58661173
Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
Contact:+86 21 5017 5386
Address:No 999,Jiangyue Rd, Minhang Dist ,201114,Shanghai ,China
Contact:+86-021-50792271
Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202
Doi:10.1055/s-1995-3918
(1995)Doi:10.1021/jo01034a021
(1964)Doi:10.1002/ardp.19683010304
(1968)Doi:10.1016/0022-328X(89)85193-9
(1989)Doi:10.1039/J19680001507
()Doi:10.1021/ja01300a054
(1936)
