
Tetrahedron Letters p. 3933 - 3936 (1995)
Update date:2022-08-05
Topics:
Guanti, Giuseppe
Riva, Renata
The AB ring system 2 of aklavinone 1 was obtained using a chemoenzymatic protocol.Key steps are the stereoselective addition of lithium enolate of ethyl acetate to ketone 13 and the intramolecular Freiedel-Crafts reaction to give tetralin 17.
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