(E) and (Z)-β-Fluoromethylene-m-Tyrosines: Resolution and Determination of Configuration

Article abstract of DOI:10.1016/0957-4166(95)00036-O

The geometrical isomers of β-fluoromethylene-m-tyrosine (E and Z) were prepared and the R and S enantiomers of the biologically active (E)-isomer were separated with an enantiomeric excess>95percent by the kinetic resolution of the racemic mixture using t