Acetal Chlorination with MnO2-Trimethylchlorosilane

DOI: 10.1016/S0040-4020(01)81231-X

Source and publish data:

Tetrahedron p. 4579 - 4586 (1992)

Update date:2022-08-03

Topics:

Authors:

Bellesia, Franco

Boni, Monica

Ghelfi, Franco

Grandi, Romano

Pagnoni, Ugo M.

Pinetti, Adriano

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Article abstract of DOI:10.1016/S0040-4020(01)81231-X

α-Chloroacetals are obtained in almost quantitative yields, by treating acetals with MnO2-trimethylchlorosilane in CH3OH:CH3CN (1:1).The halogenation is explained by a ligand-transfer process on an enolether intermediate, mediated by a Mn(IV)-chloride species.Key Words: Acetals, Aldehydes, Chlorination, Maganese(IV)oxide, Trimethylchlorosilane, Ligand-transfer

Full text of DOI:10.1016/S0040-4020(01)81231-X

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