Tandem addition-bromofunctionalization of γ,δ-unsaturated Grignard reagents to benzonitriles

DOI: 10.1055/s-1995-3908

Source and publish data:

Synthesis p. 242 - 244 (1995)

Update date:2022-08-03

Topics:

Authors:

Dechoux Dechoux

Jung Jung

Stambach

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Article abstract of DOI:10.1055/s-1995-3908

The tandem addition of but-3-enylmagnesium bromide to benzonitriles followed by electrophilic (Br⁺) trapping of the intermediate, afforded 2-aryl-5-bromomethyl-3,4-dihydro-2H-pyrroles in one step.

Full text of DOI:10.1055/s-1995-3908

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Product name:5-bromomethyl-2-(4-methoxyphenyl)-3,4-dihydro-2H-pyrrole

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