Novel antiasthmatic agents with dual activities of thromboxane A2 synthetase inhibition and bronchodilation. IV. 2-[2-(1-imidazolyl)ethyl]-4-(3-pyridyl)-1(2H)-phthalazinones

DOI: 10.1248/cpb.42.1850

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1850 - 1853 (1994)

Update date:2022-08-04

Topics:

Authors:

Yamaguchi

Koga Koga

Kamei Kamei

Akima Akima

Maruyama

Kuroki Kuroki

Hamana Hamana

Ohi Ohi

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Article abstract of DOI:10.1248/cpb.42.1850

Synthesis and pharmacological evaluation of several compounds related to 2-[2-(1-imidazolyl)ethyl]-4-(3-pyridyl)-1(2H)-phthalazinones are described. The phenyl moiety of the phthalazinone skeleton was found to play an important role in both thromboxane A<

Full text of DOI:10.1248/cpb.42.1850

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