Amplification of double stereodifferentiation in the asymmetric hydrogenation by a solvent effect

Article abstract of DOI:10.1016/0957-4166(95)00135-C

High diastereoselectivities of more than 96% leading to (S)-amino acid menthyl esters were found in the hydrogenation of both the newly prepared enantiomers 3 and 4 of menthyl (Z)-2-N-benzoylamidocinnamate with the rhodium(I)-chelate of (Ph-β-glup-OH) 1 a