Synthesis of 2,7-diazabicyclo[3.3.0]octane and 2,7-diaza bicyclo[3.3.0]oct-4-ene derivatives via cyclization reaction and Julia reaction

Article abstract of DOI:10.1080/00397919608003516

2,7-Diazabicyclo[3.3.0]octan-4-ol(1) and 2,7-diazabicyclo[3.3.0]oct-4-ene (2) are synthesized by the desulfonylation using Mg-HgCl₂(cat.) of β-hydroxy sulfone derivatives which have been prepared via cyclization of sulfone ester derivative.

Full text of DOI:10.1080/00397919608003516

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Synthesis of 2,7-
Diazabicyclo[3.3.0]octane and
2,7-Diazabicyclo[3.3.0]oct-4-
ene Derivatives via Cyclization
Reaction and Julia Reaction
Jae Wook Lee a , Ho Jung Son a , Yeon Eui Jung a &
Jae Ho Lee a
a R&D Center, Dae Woong Pharmaceutical Co., LTD ,
223-23 Sangdaewondong Sungnam, 462-120, Korea
Published online: 15 Aug 2006.
To cite this article: Jae Wook Lee , Ho Jung Son , Yeon Eui Jung & Jae Ho Lee (1996)
Synthesis of 2,7-Diazabicyclo[3.3.0]octane and 2,7-Diazabicyclo[3.3.0]oct-4-ene
Derivatives via Cyclization Reaction and Julia Reaction, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 26:8,
1499-1505, DOI: 10.1080/00397919608003516
To link to this article: http://dx.doi.org/10.1080/00397919608003516
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