Synthesis of α-Unsubstituted Aldol Adducts Utilizing Enantiomerically Pure β-Keto-δ-Dioxolane Sulfoxides

DOI: 10.1016/0040-4039(95)00853-5

Source and publish data:

Tetrahedron Letters p. 4559 - 4562 (1995)

Update date:2022-08-03

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Authors:

Blase, Frances Rose

Le, Hung

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Article abstract of DOI:10.1016/0040-4039(95)00853-5

We report an efficient means to synthesize either enantiomer of α-unsubstituted aldol adduts in high enantiomeric excess through the use of β-keto-δ-dioxolane sulfoxide 4.Through a short sequence of reactions, α-unsubstituted aldol products are obtainable in high yield.

Full text of DOI:10.1016/0040-4039(95)00853-5

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