
Chemical and Pharmaceutical Bulletin p. 1111 - 1118 (1995)
Update date:2022-08-05
Topics:
Umezawa
Nozawa
Nagumo
Akita
Three kinds of oudemansin X, (-)-1, (+)-1 and (±)-1, were totally synthesized. The key point in the present chiral synthesis was the enantioselective acetylation of the racemic alcohols, (±)-5 and (±)-8, using lipase in an organic solvent. The synthetic (-)-1 was found to exhibit strong antifungal activity against several molds and yeasts.
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Doi:10.1080/15257779508010698
(1995)Doi:10.1016/00404-0399(50)1149C-
(1995)Doi:10.1039/a909360e
(2000)Doi:10.1071/CH9951437
(1995)Doi:10.1021/ja049865t
(2004)Doi:10.1002/cplu.202100175
(2021)