Australian Journal of Chemistry p. 1437 - 1446 (1995)
Update date:2022-08-05
Topics:
Bailey, T. Sam
Bremner, John B.
Pelosi, Luciana
Skelton, Brian W.
White, Allan H.
N-Methylation of 6,7-dimethoxy-1-(2'-phenylcyclopropyl)-3,4-dihydroisoquinoline (3b) with iodomethane in refluxing acetone gave the modified Cloke rearrangement product, 8,9-dimethoxy-4-methyl-3-phenyl-2,3,5,6-tetrahydropyrrolo<2,1-a>isoquinolinium iodide (5b), a new derivative of the pyrrolo<2,1-a>isoquinoline skeleton, together with the methiodide salt (4b) of (3b).The structure of (5b) was confirmed by X-ray crystallographic analysis.
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