Nitropyrazoles 5. Synthesis of substituted 3-nitropyrazoles from 3-amino-4-cyanopyrazole

Article abstract of DOI:10.1007/BF00699193

A preparative method of synthesis of 3-nitro-4-cyanopyrazole (1) from the available 3-amino-4-cyanopyrazole was developed.Chemical conversions of 1 were studied, and 3-nitro-4-R-pyrazoles (R = CO2H, CONH2, NHCO2Me, NH2, Br, NO2), as well as 3,5-dinitro-4-methoxycarbonylaminopyrazole were obtained starting from 1.