Tetrahedron Letters p. 5637 - 5640 (1995)
Update date:2022-07-29
Topics:
Laskos
Lianis
Rodios
Terzis
Raptopoulou
1-(N,N-diaroyl)amino-4-phenyl-1,2,3-triazol-5-yl-methyltriphenylphosph onium bromide 2 reacted with potassium t-butoxide or triethylamine in dry toluene giving the very stable phosphorus ylide 5. Refluxing of 5 in xylene gave the unexpected 3-aroyl-6-aryl-pyrazolo[4,3-d][2,3]benzodiazepines 6 by a Dimroth-like rearrangement of the triazole ring and a 1,7-electrocyclization of the nitrilimine intermediate 11. When the xylene solution was not rigorously refluxed the 3(5)-aroyl-5(3)-phenyl pyrazole 7 was isolated. The x-ray crystal structures of compounds 5d and 6b are also given.
View MoreContact:0792-8228321
Address:10TH Floor No.121 binjiang Road Xunyang District
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd
Contact:+86-311-80817929
Address:Shangzhuang,Shijiazhuang,China
Yancheng Creator Chemical Co., Ltd
Contact:0086-515-88710008 88710068 88710858 88710868
Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Shanghai Sharing technologies Co., Ltd.
Contact:86-021-66787223
Address:No11, Lane 225, Jinxiang Road,Pudong district
Jinan Decheng Hemu Medical Technology Co.,Ltd.
Contact:+86-531-68650525
Address:NO.554 Zhengfeng Road High-new Technology Development Zone
Doi:10.1039/c39950002275
(1995)Doi:10.1007/BF00475534
()Doi:10.1039/jr9380000545
(1938)Doi:10.1039/b602536f
(2006)Doi:10.1055/s-1995-4037
(1995)Doi:10.1021/om000223y
(2000)