Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches

DOI: 10.1016/j.bioorg.2021.104877

Source and publish data:

Bioorganic Chemistry (2021)

Update date:2022-09-26

Topics:

Authors:

Boraei, Ahmed T.A.

Eltamany, Elsayed H.

Ali, Ibrahim A.I.

Gebriel, Sara M.

Nafie, Mohamed S.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bioorg.2021.104877

Liver cancer is the most common type of cancer in many countries. New studies and statistics show rising liver cancer worldwide, so it is essential to seek new agents for this type of cancer. PIM1 has an attractive target in the discovery of cancer medica

Full text of DOI:10.1016/j.bioorg.2021.104877

Products guided by the article

Product name:6-(4-aminophenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile

Cas No:171071-00-4

R&D Labs maybe for 171071-00-4

Sichuan WeiKeqi Biological Technology Co., Ltd.

website:https://www.weikeqi-biotech.com/en

Contact:86-028-81700200

Address:sichuan Chengdu Qingjiang Zhonglu 63号
Jiaxing Barton Chemicals

website:http://www.chinabarton.com

Contact:+86-573-82719618

Address:No. 162 Fumin Road, Honghe Town,
Jiaxing Anrui Material Technology Co., Ltd.

Contact:86-573-82651652 13305832579

Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
nanjing suru chemical co.ltd

Contact:+86-025-52406782

Address:8 Taizishan Rd., Yanjiang Industrial Development Area, Nanjing, Jiangsu, China.
Chengdu Sino-Strong Pharmaceutical Co.,Ltd.

website:http://www.sino-strong.com.cn

Contact:+86-28-82666753

Address:459 West haike road,Cross-straits technological industry park, Wenjiang district,Chengdu, P.R.China

Relevant to this article

Discovery of deoxyceramide analogs as highly selective ACER3 inhibitors in live cells

Doi:10.1016/j.ejmech.2021.113296
(2021)
Alkoxycarbonyl groups transfer to amines by the N,N'-dibenzyl- and N,N'-di-tert-butyl-carbamates of cyclic thioureas

Doi:10.1039/P19950002953
(1995)
Synthetic Applications of the Carbanion with a Fluoroalkyl Group Generated by Palladium(0) Catalyst under Neutral Conditions

Doi:10.1021/jo990463r
(1999)
RES-1149-1 and -2, novel non-peptidic endothelin type B receptor antagonists produced by Aspergillus sp. II. Structure determination and derivatization

Doi:10.7164/antibiotics.49.6
(1996)
Discovery and structure-activity relationship of 1,3-cyclohexyl amide derivatives as novel mGluR5 negative allosteric modulators

Doi:10.1016/j.bmcl.2012.12.078
(2013)
Nuclear magnetic resonance studies of sulfur compounds. II. The substituent effect on geminal coupling constants and on magnetic nonequivalence of the methylene protons of sulfoxides.

Doi:10.1248/cpb.15.1669
(1967)

Article Doi