Discovery of deoxyceramide analogs as highly selective ACER3 inhibitors in live cells

DOI: 10.1016/j.ejmech.2021.113296

Source and publish data:

European Journal of Medicinal Chemistry (2021)

Update date:2022-09-26

Topics:

Authors:

Bielsa, Núria

Casasampere, Mireia

Aseeri, Mazen

Casas, Josefina

Delgado, Antonio

Abad, José Luis

Fabriàs, Gemma

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Article abstract of DOI:10.1016/j.ejmech.2021.113296

Acid (AC), neutral (NC) and alkaline ceramidase 3 (ACER3) are the most ubiquitous ceramidases and their therapeutic interest as targets in cancer diseases has been well sustained. This supports the importance of discovering potent and specific inhibitors

Full text of DOI:10.1016/j.ejmech.2021.113296

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