New solid phase synthesis of oligodeoxythymidine phosphorodithioates by a modified HObt-method

DOI: 10.1016/0040-4039(95)01106-R

Source and publish data:

Tetrahedron Letters p. 6127 - 6130 (1995)

Update date:2022-08-05

Topics:

Authors:

Eldrup, Anne B.

Felding, Jakob

Kehler, Jan

Dahl, Otto

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Article abstract of DOI:10.1016/0040-4039(95)01106-R

Two new dithiophosphorylating reagents 2a,b have been prepared and shown to give nucleoside monomers 3a,b with reactivities suitable for solid phase synthesis. An octamer and a nonamer deoxythymidine phosphorodithioate were prepared on a TentaGel support

Full text of DOI:10.1016/0040-4039(95)01106-R

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