Tetrahedron p. 10361 - 10374 (1995)
Update date:2022-08-02
Topics:
Martin-Martinez, Mercedes
Garcia-Lopez, M. Teresa
Herranz, Rosario
Rosario, Gonzalez-Muniz
The synthesis of 4,7-di- and 4,7,7-trisubstituted 3,6-dioxoperhydropyrrolo[1,2-a]pyrazine-7-carboxylate derivatives is described. The approach used for the preparation of this heterocyclic template is based on the reductive amination of 4-ketodiesters derived from dipeptides.
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