Addition of functionalized zinc copper reagents to acetylenic esters: Synthesis of 2-carboalkoxy cyclohexenones

DOI: 10.1016/0040-4039(95)01485-Z

Source and publish data:

Tetrahedron Letters p. 7061 - 7064 (1995)

Update date:2022-08-02

Topics:

Authors:

Crimmins, Michael T.

Huang, Sujuan

Guise, Lisa E.

Borden Lacy

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01485-Z

Conjugate addition of the zinc-copper reagent derived from ethyl 4-iodobutyrate to acetylenic esters in the presence of TMSCl and HMPA results in cyclization and formation of 3-alkyl-2-carboalkoxycyclohexenones in good yields.

Full text of DOI:10.1016/0040-4039(95)01485-Z

Products guided by the article

Product name:2-(1-Methoxymethoxy-hex-5-enyl)-6-oxo-cyclohex-1-enecarboxylic acid ethyl ester

Cas No:172091-70-2

R&D Labs maybe for 172091-70-2

Taixing Joxin Bio-tec Co.,Ltd.

website:http://www.joxbio.com

Contact:86-523-87558858 87612088

Address:No.88, chengdong industrial park
Zhejiang Chemline International Co., Ltd.

Contact:+86-571-88062298

Address:Hengdian Industry Area, Dongyang, Zhejiang, China
shijiazhuang shuanglian chemical industry co.,ltd

Contact:0311-82190302

Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
Shantou Baokang Pharmaceutical Co., Ltd.

Contact:+86-754-88873487

Address:5/F B Block Huangshan Bldg Huangshan Rd Shantou
Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Contact:86-180510-83338

Address:Suite# 210, No. 1 BuildingNanjing Agricultural Biotechnology High-tech Entrepreneurship Center, No. 4 Tongwei Road, Xuanwu District, Nanjing,China

Relevant to this article

Synthesis of a novel bis-gluco-crown ether derivative

Doi:10.1080/00397919508011451
(1995)
Efficient routes to cyclic 2,3-epoxyalcohols from cycloalkenyl ketones, via cycloalkenyl alcohols

Doi:10.1016/S0040-4020(01)80560-3
(1993)
An improved synthetic preparation of anti conformationally constrained acyclic nucleosides

Doi:10.1081/SCC-100103324
(2001)
HIGHLY DIASTEREOSELECTIVE REDUCTIONS OF N-DIPHENYLPHOSPHINYL IMINES. SYNTHESIS OF AXIAL PRIMARY CYCLIC AMINES.

Doi:10.1016/S0040-4039(00)96795-9
(1987)
Design, synthesis and properties of orthopalladated complexes: Proheterogeneous catalyst

Doi:10.1016/j.poly.2016.02.024
(2016)
Preparation of Cationic (E)-?-Alkenyl Palladium Complexes having a P-O-N or a P-O-P Tridentate Ligand as a Stabilized Intermediate of Palladium-catalysed Stereoselective Addition of Methanol to Acetylenes; Characterisation, X-Ray Analysis and the Reaction Pathway

Doi:10.1039/c39950002099
(1995)

Article Doi