A Formal Total Asymmetric Synthesis of (+)-Thienamycin

DOI: 10.1016/0957-4166(95)00327-L

Source and publish data:

Tetrahedron Asymmetry p. 2507 - 2510 (1995)

Update date:2022-08-04

Topics:

Authors:

Davies, Stephen G.

Hedgecock, Charles J. R.

McKenna, Jeffrey M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(95)00327-L

Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly diastereoselective Michael addition of a differentially protected lithium amide.

Full text of DOI:10.1016/0957-4166(95)00327-L

Products guided by the article

Product name:(E)-(S)-3-[Allyl-((R)-1-phenyl-ethyl)-amino]-5-trimethylsilanyl-pent-4-enoic acid tert-butyl ester

Cas No:171672-71-2

R&D Labs maybe for 171672-71-2

Hunan Dinuo Pharmaceutical Co.,Ltd.

Contact:86-731-88280100*8561

Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
Aminodiscovery Co.,Ltd.

Contact:+86-535-8888888

Address:No.161 Haishi Rd.
Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Baoding City Light Industry And Textiles Imp.& Exp. Corp. Chemical Department.

Contact:86-312-3262436

Address:NO.658 CHAOYANG SOUTH STREET,BAODING CITY HEBEI CHINA
Jitat Company Ltd

Contact:852-27701081

Address:Room 2509, New Tech Plaza, 34 Tai Yau St., San Po Kong, HK

Relevant to this article

Fluorination of methyl 6-deoxy-1-thiohexopyranosides with diethylaminosulfur trifluoride (DAST), and the formation of unexpected products

Doi:10.1016/0008-6215(93)84076-I
(1993)
Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease

Doi:10.1021/jo00129a037
(1995)
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin

Doi:10.1021/acs.jmedchem.0c01809
(2021)
Convenient synthesis of N1-substituted orotic acid derivatives

Doi:10.1016/j.tetlet.2014.10.005
(2014)
A new series of pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors

Doi:10.1021/jm00023a007
(1995)
Synthesis of Tn and Sialyl Tn Building Blocks for Solid Phase Glycopeptide Synthesis

Doi:10.1016/0040-4039(95)01515-9
(1995)

Article Doi