
Tetrahedron p. 12963 - 12970 (1995)
Update date:2022-07-30
Topics:
Chordia, Mahendra D.
Gharpure, Milind M.
Kingston, David G. I.
Two facile B ring cleavage reactions of taxoids related to paclitaxel are reported. Treatment of a 13-chlorobaccatin with azide ion led to cleavage of the C-10/C-11 bond and formation of a hemiketal product. Treatment of a protected 2-debenzoyl paclitaxel with MnO2 yielded a ketoaldehyde in which the C-1/C-2 bond had been cleaved and the side chain had been eliminated.
View MoreContact:+44 (0)2036089360-31
Address:Chanceryhouse,Chancery Lan
Beijing Top Science biological technology co., LTD
Contact:+86-13439059536
Address:15-1705 jre three mile, Beijing 100000,CHINA
Shanghai united Scientific Co.,Ltd.
Contact:+86-21-53535353
Address:28F No.900 huaihai Road Shanghai China
Changsha Yonta Industry Co., Ltd.
Contact:+ 86-731-8535 2228
Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
website:http://www.eastarchem.com/
Contact:1-800-898-2436
Address:1215 K Street, STE 1700
Doi:10.1016/0301-0104(88)87115-5
(1988)Doi:10.1002/hlca.19980810532
(1998)Doi:10.1021/np800303t
(2008)Doi:10.1021/jo01274a021
(1968)Doi:10.1021/jm950616c
(1996)Doi:10.1007/BF00908908
(1968)