Free radical-mediated intermolecular conjugate additions. Effect of the lewis acid, chiral auxiliary, and additives on diastereoselectivity

DOI: 10.1021/ja991205e

Source and publish data:

Journal of the American Chemical Society p. 7517 - 7526 (1999)

Update date:2022-08-05

Topics:

Authors:

Sibi, Mukund P.

Ji, Jianguo

Sausker, Justin B.

Jasperse, Craig P.

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Article abstract of DOI:10.1021/ja991205e

We have developed a highly diastereoselective method for the conjugate addition of carbon radicals to chiral α,β-unsaturated N-enoyloxazolidinones using Bu₃SnH as chain carrier and Et₃B/O₂ as radical initiator. Lewis acids

Full text of DOI:10.1021/ja991205e

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