Tetrahedron Letters p. 7143 - 7146 (1999)
Update date:2022-07-30
Topics:
Bew, Sean P.
Bull, Steven D.
Davies, Stephen G.
Eames, Jason
Baxter, Anthony D.
Mykytiuk, John
The bis-enolate derived from 1,3-di-isobutyryl-trans-4,5-tetramethylene- imidazolidin-2-one 8 is unstable and deacylates to afford dianion 11 which can be regioselectively alkylated to afford unsymmetric cyclic urea 17 in good yield. Subsequent deacylatio
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