An Efficient and Stereospecific Synthesis of Novel Pyrazine C-nucleosides

DOI: 10.1016/0040-4039(95)01826-4

Source and publish data:

Tetrahedron Letters p. 8363 - 8366 (1995)

Update date:2022-07-30

Topics:

Authors:

Chen, Jiong J.

Walker, John A.

Liu, Weimin

Wise, Dean S.

Townsend, Leroy B.

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Article abstract of DOI:10.1016/0040-4039(95)01826-4

A novel 2'-deoxy-β-D-ribofuranosyl pyrazine C-nucleoside (6) was synthesized via a stereospecific palladium(0)-mediated cross-coupling reaction.The β-configuration of this nucleoside was established by NOE analysis and the formation of a 5,5'-anhydro nucl

Full text of DOI:10.1016/0040-4039(95)01826-4

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Product name:3-[(2R,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,5-dihydro-furan-2-yl]-5-chloro-pyrazine-2,6-diamine

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