Total Synthesis of Milbemycin G: Assembly and Completion of the Synthesis

DOI: 10.1039/c39950002521

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 2521 - 2522 (1995)

Update date:2022-08-03

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Authors:

Bailey, Simon

Teerawutgulrag, Aphiwat

Thomas, Eric J.

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Article abstract of DOI:10.1039/c39950002521

The Wittig reaction between phosphonium salt 1 and the hydroxybutenolide 2 followed by deprotection, macrocyclisation, and reduction gives the 6-hydroxymilbemycin E 9 which by further cyclisation is converted into milbemycin G 11.

Full text of DOI:10.1039/c39950002521

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