Partial deacetylation of asterriquinone diacetate by aqueous sodium bicarbonate in pyridine

Article abstract of DOI:10.1248/cpb.43.1818

Asterriquinone (ARQ); 2,5 -bis[1-(1,1-dimethyl-2-propenyl)-1H-indol-3- yl]-3,6-dihydroxy-2,5-cyclohexadiene-1,4-dione and ARQ monoacetate are metabolites from mycelium of Aspergillus terreux IFO 6123. ARQ diacetate was convened into ARQ monoacetate by treatment with 5% aq. NaHCO₃ in pyridine at 80°C for 5 min, and the yield was 93.4%. Similarly, by treatment with 5% aq. NaHCO₃ in acetone at room temperature, 2,5-diacetoxy-p-xyloquinone and 2,5- diacetoxy-p-benzoquinone were convened into 2-acetoxy-5-hydroxy-p-xyloquinone (yield, 85.8%) and 2-acetoxy-5-hydroxy-p-benzoquinone (yield, 66.7%), respectively.

Full text of DOI:10.1248/cpb.43.1818

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