Synthesis and alkylation of N-methylmorpholinium 6-amino-3,5-dicyano-4-methylpyridine-2-thiolate

Article abstract of DOI:10.1007/BF02503784

The condensation of acetaldehyde with a twofold excess of cyanothioacetamide and N-methylmorpholine gives N-methylmorpholinium 6-amino-3,5-dicyano-4-methylpyridine-2-thiolate. This compound is also formed by recyclization of 2,6-diamino-3,5-dicyano-4-methyl-4H-thiopyran. From this pyridinethiolate, several substituted 2-alkylthiopyridines and 3,6-diamino-5-cyano-4-methyl-2-methoxycarbonylthieno[2,3-b]pyridine were obtained.