The synthesis of enantiomerically pure (2R)-α-methylisoserine

DOI: 10.1016/0040-4020(95)00919-1

Source and publish data:

Tetrahedron p. 687 - 694 (1996)

Update date:2022-08-03

Topics:

Authors:

Cativiela, Carlos

Diaz-De-Villegas, Maria D.

Galvez, Jose A.

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Article abstract of DOI:10.1016/0040-4020(95)00919-1

The title compound was prepared by diastereoselective methylation of chiral (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl acetoxycyanoacetate and subsequent nitrile hydrogenation.

Full text of DOI:10.1016/0040-4020(95)00919-1

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Product name:Nitrooxy-acetic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester

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