Journal of the Chemical Society. Perkin transactions II p. 825 - 828 (1980)
Update date:2022-08-03
Topics:
Senogles, Ernest
Thomas, Roderick A.
The kinetics and mechanism of the acid-catalysed hydrolysis of N-vinylpyrrolidin-2-one (1) has been studied using n.m.r. spectroscopy and spectrophotometry.At temperatures near 0 deg C N-(1-hydroxyethyl)pyrrolidine-2-one (3) is the main product.At higher temperatures this decomposes into acetaldehyde and pyrrolidin-2-one (4) and the latter reacts with an excess of N-vinylpyrrolidine-2-one to give 1,1-bis-(N-2-oxopyrrolidinyl)ethane (5).The rate determining step of the hydrolysis reaction has been established as proton transfer to N-vinylpyrrolidin-2-one and the reaction conforms to a general acid catalysis mechanism.A Broensted exponent value of 0.68 +/- 0.03 was obtained with a series of carboxylic acids.
View MoreContact:+44 (0)2036089360-31
Address:Chanceryhouse,Chancery Lan
NINGBO YINLIANG FOREIGN TRADE CO., LTD.
Contact:+86-574-87834016 / 87898057
Address:23F NO.666JINYU ROAD,YINGZHOU DISTRICT,NINGBO.CHINA
Contact:+86-571-86491666
Address:SHI XIANG ROAD
Jiangsu Taihu New Materials Holding Co., Ltd
Contact:+86-519-86160108
Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Contact:+86 021-51698675
Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China
Doi:10.1016/S0040-4020(99)00680-8
(1999)Doi:10.1021/ja953976y
(1996)Doi:10.1246/bcsj.69.289
(1996)Doi:10.1021/jo951526i
(1996)Doi:10.1016/0968-0896(96)00082-X
(1996)Doi:10.1002/anie.200462101
(2005)