Salen-anthraquinone conjugates. Synthesis, DNA-binding and cleaving properties, effects on topoisomerases and cytotoxicity

DOI: 10.1016/0968-0896(96)00082-X

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1185 - 1196 (1996)

Update date:2022-08-03

Topics:

Authors:

Routier, Sylvain

Cotelle, Nicole

Catteau, Jean-Pierre

Bernier, Jean-Luc

Waring, Michael J.

Riou, Jean-Francois

Bailly, Christian

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Article abstract of DOI:10.1016/0968-0896(96)00082-X

A series of amidoethylamino-anthraquinone derivatives bearing either one or two salen (bis(salicylidene) ethylenediamine) moieties complexed with Cu(II) or Ni(II) have been synthesized, and their DNA-binding and cleaving properties examined. The effects o

Full text of DOI:10.1016/0968-0896(96)00082-X

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