A novel furan ring construction and syntheses of 4- and 4,5-substituted 2-(α-heterocycloalkyl)furans

Article abstract of DOI:10.1021/jo00108a028

4-Substituted and 4,5-disubstituted 2-(benzotriazol-1-ylmethyl)furans 3 have been prepared in good yields from 1-propargylbenzotriazole (1) and α-bromo ketones via one-pot processes. The 2-(benzotriazol-1-ylmethyl) side chain of 3 was alkylated by lithiat