Indolizidine derivatives as potential substance P antagonists

DOI: 10.1016/0960-894X(95)00581-D

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 161 - 164 (1996)

Update date:2022-07-30

Topics:

Authors:

Chan, Chuen

Cocker, J. Derek

Davies, H. Geoffrey

Gore, Andrea

Green, Richard H.

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Article abstract of DOI:10.1016/0960-894X(95)00581-D

Two novel indolizidine analogues, (7a) and (7b), of the substance P antagonist CP 99,994 have been prepared. Possible conformational factors for their low biological activity are discussed.

Full text of DOI:10.1016/0960-894X(95)00581-D

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Product name:2-Methylene-8a-phenyl-hexahydro-indolizine-5,8-dione

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