
Tetrahedron Letters p. 973 - 976 (1996)
Update date:2022-08-03
Topics:
Jin, Yi
Biancotto, Giancarlo
Just, George
1,2-Di-O-cyclopentylidene-5-isopropylamino-D-xylofuranose 4 and its enantiomer ent-4 were used as chiral auxiliaries to form, respectively, Rp and Sp dinucleotide phosphorothioates 11 and 12 in 98% diastereomeric excess, using phosphoramidite methodology and 2-bromo-4,5-dicyanoimidazole as catalyst.
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