Deamination of 9-(hydroxymethylated cycloalkyl)-9H-adenines (carbocyclic adenine nucleosides) by adenosine deaminase: Effect of high-pressure upon deamination rate and enantioselectivity

Article abstract of DOI:10.1080/07328319608002411

The deamination of eight kinds of racemic carbocyclic adenine nucleosides by adenosine deaminase under high-pressure (400 MPa) was examined and the result was compared with that obtained from the reaction under atmospheric pressure. The deamination of all

Full text of DOI:10.1080/07328319608002411

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Nucleosides and Nucleotides
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Deamination of 9-(Hydroxymethylated
cycloalkyl)-9H-adenines (Carbocyclic
Adenine Nucleosides) by Adenosine
Deaminase: Effect of High-Pressure
Upon Deamination Rate and
Enantioselectivity
Nobuya Katagiri a , Yumiko Ito a , Takuya Shiraishi a , Tokumi
Maruyama b , Yoshiko Sato b & Chikara Kaneko a
a Pharmaceutical Institute, Tohoku University , Aobayama, Aoba-
ku, Sendai, 980-77, Japan
b Faculty of Pharmaceutical Sciences, Tokushima Bunri
University , Yamashiro-cho, Tokushima, 770, Japan
Published online: 21 Aug 2006.
To cite this article: Nobuya Katagiri , Yumiko Ito , Takuya Shiraishi , Tokumi Maruyama , Yoshiko
Sato & Chikara Kaneko (1996) Deamination of 9-(Hydroxymethylated cycloalkyl)-9H-adenines
(Carbocyclic Adenine Nucleosides) by Adenosine Deaminase: Effect of High-Pressure Upon
Deamination Rate and Enantioselectivity , Nucleosides and Nucleotides, 15:1-3, 631-647
To link to this article: http://dx.doi.org/10.1080/07328319608002411
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