Tetrahedron Letters p. 1707 - 1710 (1996)
Update date:2022-07-29
Topics:
Jones, Raymond C. F.
Howard, Kevin J.
Snaith, John S.
The synthesis of either enantiomer of 1-benzyl-4-phenyl-2-imidazoline from phenylglycine is described. 'One-pot' generation and enantioselective 1,3-dipolar cycloaddition of homochiral azomethine ylides prepared from these imidazolines with a range of alkene dipolarophiles affords optically active hexahydropyrroloimidazole adducts.
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