Bioorganic and Medicinal Chemistry Letters p. 615 - 618 (1996)
Update date:2022-07-29
Topics:
Taillefumier
De Fornel
Chapleur
The coupling of metalated pyridine derivatives with a chiral Weinreb amide derived from gluconolactone followed by stereoselective reduction of the resulting ketone are the key steps of the synthesis of bisubstrates analogues of the HMGCoA reduction by HMGR.
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