Synthesis and mode of action of 1-substituted trans-cyclopropane 1,2-dicarboxylic acids: Inhibitors of the methylaspartase reaction

DOI: 10.1039/cc9960000675

Source and publish data:

Chemical Communications p. 675 - 677 (1996)

Update date:2022-08-03

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Authors:

Badiani, Kamal

Lightfoot, Philip

Gani, David

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Article abstract of DOI:10.1039/cc9960000675

A range of 1-substituted cyclopropane 1,2-dicarboxylic acids are synthesised using short efficient routes and are found to be good to potent inhibitors of 3-methylaspartase; the crystallographically determined absolute stereochemistry and the mode of acti

Full text of DOI:10.1039/cc9960000675

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