Synthesis of the interferon-α inducer imiquimod by thermal electrocyclic reactions of 1- and 2-azahexatriene systems

DOI: 10.1248/cpb.44.709

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 709 - 714 (1996)

Update date:2022-08-05

Topics:

Authors:

Yoshioka, Haruyuki

Matsuya, Yuhji

Choshi, Tominari

Sugino, Eiichi

Hibino, Satoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.44.709

The interferon-α inducer imiquimod (1), possessing an imidazo[4,5- c]quinoline ring, has been newly synthesized by two routes on thermal electrocyclic reactions of 1- and 2-azahexatriene systems involving the imidazole 4,5-bond.

Full text of DOI:10.1248/cpb.44.709

NII-Electronic Library Service

Products guided by the article

Product name:2-(3-Isobutyl-2-methylsulfanyl-3H-imidazol-4-yl)-benzoic acid methyl ester

Cas No:177212-74-7

R&D Labs maybe for 177212-74-7

ZHEJIANG CHEMICAL INDUSTRY INSTITUTE TECHNOLOGY CO.,LTD(expird)

Contact:86-575-82730298

Address:shangyu
SuZhou Yacoo Science Co., Ltd

Contact:86-512-87182055

Address:No.128 Fangzhou Rd, Suzhou Industrial Park, China, 215125, China
Laizhou City Laiyu Chemical CO.,Ltd

Contact:+86-535-2719337/2719339

Address:Chenggang road zhuyou laizhou City Shangdong China
SuZhou LaiTeou

Contact:+86-0512-88957371

Address:shanghai
Liao Cheng All Win Chemicals Co.,LTD

Contact:86+0635-2991582

Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China

Relevant to this article

Fe²⁺-catalyzed formation of nitriles and thionamides from intact glucosinolates

Doi:10.1021/np070438d
(2008)
Doi:10.1039/j39690001758
(1969)
Doi:10.1021/jo00969a018
(1972)
Doi:10.1021/jo00831a070
(1970)
Synthesis of 3-C-(methyl β-D-xylofuranosid-3-yl)-5-phenyl-1,2,4-oxadiazole

Doi:10.1016/S0008-6215(99)00106-8
(1999)
A novel sulfinylation of alkenes by tosyl cyanide with titanium(IV) chloride

Doi:10.1016/S0040-4039(99)00894-1
(1999)

Article Doi