Bioorganic and Medicinal Chemistry Letters p. 763 - 766 (1996)
Update date:2022-08-03
Topics:
Annoura, Hirokazu
Fukunaga, Atsuko
Uesugi, Mayumi
Tatsuoka, Toshio
Horikawa, Yoshiko
7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates (4a-c), highly potent antagonists for a phospholipase C-linked metabotropic glutamate receptor, mGluR1, were synthesized through cyclopropanation onto 4-oxo-4H-1-benzopyran-2-carboxylates (5a-c) utilizing dimethyloxosulfonium methylid followed by treatment with hydroxylamine.
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Doi:10.1039/dt9960002089
(1996)Doi:10.1016/0022-328X(95)06046-Y
(1996)Doi:10.1021/jm960142x
(1996)Doi:10.1002/jhet.5570330215
(1996)Doi:10.1021/ja01003a030
(1968)Doi:10.1002/aoc.6292
(2021)
