Synthesis of polysubstituted anilines using the Diels-Alder reaction of methyl 5-aminofuroate

DOI: 10.1016/0040-4039(96)00440-6

Source and publish data:

Tetrahedron Letters p. 2903 - 2906 (1996)

Update date:2022-08-02

Topics: Diels-Alder Reaction

Authors:

Cochran, John E.

Wu, Tianhua

Padwa, Albert

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Article abstract of DOI:10.1016/0040-4039(96)00440-6

Methyl 5-aminofuroate undergoes a facile [4+2]-cycloaddition with a variety of dienophiles to afford ring opened cycloadducts which are readily dehydrated using BF₃·OEt₂ to give polysubstituted anilines.

Full text of DOI:10.1016/0040-4039(96)00440-6

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