Cyclic peptides from higher plants. XXVIII. Antitumor activity and hepatic microsomal biotransformation of cyclic pentapeptides, astins, from Aster tataricus

DOI: 10.1248/cpb.44.1026

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Chemical and Pharmaceutical Bulletin p. 1026 - 1032 (1996)

Update date:2022-07-30

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Authors:

Morita, Hiroshi

Nagashima, Shinji

Uchiumi, Yuki

Kuroki, Osamu

Takeya, Koichi

Itokawa, Hideji

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Article abstract of DOI:10.1248/cpb.44.1026

Antitumor activities on Sarcoma 180A of a series of cyclic pentapeptides, astins, isolated from the roots of Aster tataricus, were examined. The activities on various congeners of the dichlorinated proline residues prepared by chemical conversion and a he

Full text of DOI:10.1248/cpb.44.1026

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