Synthesis of a model bicyclic C-O-D-O-E ring of vancomycin by a one-pot, double SNAr based macrocyclization

DOI: 10.1039/cc9960001029

Source and publish data:

Chemical Communications p. 1029 - 1030 (1996)

Update date:2022-07-30

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Authors:

Beugelmans, Rene

Bois-Choussy, Michele

Vergne, Caroline

Bouillon, Jean-Philippe

Zhu, Jieping

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Article abstract of DOI:10.1039/cc9960001029

Double cyclization of linear pentapeptide 3 by treatment with CsF in DMF at -5°C gives a model bicyclic CODOE ring 2 of vancomycin in a one-pot fashion.

Full text of DOI:10.1039/cc9960001029

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