Bioorganic and Medicinal Chemistry Letters p. 1371 - 1374 (1996)
Update date:2022-08-03
Topics:
Han, Qi
Lafontaine, Jennifer
Bacheler, Lee T.
Rayner, Marlene M.
Klabe, Ronald M.
Erickson-Viitanen, Susan
Lam, Patrick Y.S.
Several bis-N-alkylated (+)-biotin derivatives were synthesized and evaluated for activities against HIV-1 protease. The most potent inhibitor, 2D, synthesized in two steps from (+)-biotin, has K(i) of 0.50 μM and antiviral IC90 of 7 μM. The (+
View MoreBeijing Stable Chemcial Co.ltd
Contact:86-10-63785052
Address:A1301 Technological Edifice. No.4 FuFeng Road,FengTai District, Beijing. China
Contact:18710867521(wechat)
Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China
RongCheng Tianyu Technology Co.,Ltd.
Contact:86-631-7519595
Address:220Ping Donghai Road RongChengCity,ShangDong Province China
Sichuan Highlight Fine Chemicals Co., Ltd.
Contact:+86-28-8525 1605
Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section
Jinan Jinguilin Chemical Co.,Ltd
Contact:+86-531-81188412
Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Doi:10.1021/ol0270024
(2002)Doi:10.1002/hlca.19910740829
(1991)Doi:10.1039/c39910001707
(1991)Doi:10.1002/hlca.19910740830
(1991)Doi:10.1016/0031-9422(91)80103-8
(1991)Doi:10.1021/jm00324a027
(1966)