Tetrahedron Letters p. 4289 - 4292 (1996)
Update date:2022-07-29
Topics:
Macor, John E.
Ogilvie, Ron J.
Wythes, Martin J.
Utilizing a 2,6-dibromoaniline (6b) in place of the original monobromo aniline in the indole-forming intramolecular Heck reaction allows for a greater than two-fold improvement in the overall yield of CP-122,288. The second bromine is carried through unmolested, forming a 7-bromoindole analog of CP-122,288 (1b). This result might represent a novel approach to 7- substituted indole derivatives.
View MoreYangzhou Zhongbao Pharmaceutical Co.,Ltd
Contact:+86-514-88290838
Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Contact:+86-15850770348
Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China
Jining tiansheng chemical co.,ltd.
Contact:+86-537-5158722
Address:ROOM 1011, BLOCK B, CUIDU INTERNATIOAL BUSINESS CENTER, JINING CITY, CHINA
Fujian Wanke Pharmaceutical Co., LTD.
Contact:+86-598-5026002
Address:Economic development zone,jiangle county
Nanjing Qirui Material Co., Ltd.
Contact:+86-25-52320053
Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
Doi:10.1002/oms.1210030810
(1970)Doi:10.1016/j.tetlet.2006.04.141
(2006)Doi:10.1002/oms.1210021205
(1969)Doi:10.1039/c7cc03229c
(2017)Doi:10.1016/0040-4039(96)01026-X
(1996)Doi:10.1021/jm960409s
(1996)
