Enzymatic hydrolysis of meso(syn-syn)-1,3,5-triacetoxy-2,4- dimethylpentane and acetylation of meso(syn-syn)-3-benzyloxy-2,4- dimethylpentane-1,5-diol by lipase

DOI: 10.1248/cpb.44.1391

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1391 - 1394 (1996)

Update date:2022-08-04

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Authors:

Nagumo, Shinji

Arai, Takayuki

Akita, Hiroyuki

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Article abstract of DOI:10.1248/cpb.44.1391

Chiral inductions of meso triacetate (4) and meso diol (15) were carried out on the basis of enzymatic reaction using lipase to give chiral synthons having three consecutive chiral centers with high enantiomeric excess.

Full text of DOI:10.1248/cpb.44.1391

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