Synthesis and biological evaluation of 4-alkoxy substituted trinems. Part 1

DOI: 10.1016/0960-894X(96)00359-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2019 - 2024 (1996)

Update date:2022-09-26

Topics:

Authors:

Andreotti, Daniele

Biondi, Stefano

Di Fabio, Romano

Donati, Daniele

Piga, Elisabetta

Rossi, Tino

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Article abstract of DOI:10.1016/0960-894X(96)00359-9

Synthesis of new 4-alkoxy substituted trinems 4, 5, 6, 7 and 8 together with their antibacterial profiles compared to imipenem and GV104326 (2) are described. The good antibacterial profile observed for derivatives 4-7 encouraged further exploration of these derivatives.

Full text of DOI:10.1016/0960-894X(96)00359-9

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